Ostenil injection for osteoarthritis with hyaluronic acid, rheumatology sports medicine

Pre-filled syringe 2 ml

OSTENIL® PLUS is indicated to relieve pain and improve mobility in degenerative and traumatic changes of synovial joints. Viscoelastic solution for injection in the joint cavity. High concentration.

The aim of the injection is to increase the concentration of hyaluronic acid in the joint, which often decreases as a result of osteoarthritis. The structure of the hyaluronic acid contained in OSTENIL®, OSTENIL® PLUS and OSTENIL® MINI matches that of the natural hyaluronic acid in the human body.

OSTENIL® PLUS: pre-filled syringe to relieve pain induced by osteoarthritis. Effective, safe and very well-tolerated.

  • 2% hyaluronic acid obtained by biofermentation
  • 0.5% mannitol
  • Single injection with flexible treatment scheme
  • For all synovial joints


Registered under Act 737
MDA Reg. No. GD21107614918



Main ingredient

Pre-filled syringe 2 ml 2% Hyaluronic acid 

Inject OSTENIL® PLUS into the affected joint once a week for a total of 1–3 injections. Several joints may be treated at the same time. Repeat treatment cycles may be administered as required. In case of joint effusion, it is advisable to reduce the effusion by aspiration, rest, application of an ice pack and/or intraarticular corticosteroid injection. Treatment with OSTENIL® PLUS can be started two to three days later. The content and the outer surface of the OSTENIL® PLUS pre-filled syringe are sterile as long as the sterile pack is intact. Take the pre-filled syringe out of the sterile pack, unscrew the Luer lock cap from the syringe, attach a suitable needle (for example 18 to 25 G) and secure it by turning slightly. Remove any air bubble, if present, before injection.

For doctor use only

Ostenil joint pain acid hayluronic-TRB-Chemedica-EN-570×370

Proven to be effective

  • Relieves pain1-3
  • Improves mobility1-3
  • Reduces use of painkillers4
  • High level of satisfaction among patients: around 90% of patients were satisfied with the result of treatment5
  • Treatment with OSTENIL® PLUS is suitable for any synovial joint

Safe and well-tolerated

  • Terminal sterilisation by autoclave (SAL6)
  • Hyaluronic acid obtained by biofermentation
  • Free from animal protein
  • Optimal molecular weight
  • Structure matches the natural hyaluronic acid contained in human body